Have your cardiomyocytes been characterized using patch clamp electrophysiology?
Ma et al. (2011) provided in-depth characterization data on iCell® Cardiomyocytes using the manual perforated patch clamp method. iCell Cardiomyocytes recapitulate the electrophysiological characteristics of native human cardiomyocytes, expressing cardiac Na+, Ca2+, and K+ channels and enabling cardiac action potential recording for electrophysiological interrogation.
- iCell Cardiomyocytes User's Guide
- Application Protocol: Measuring Cardiac Electrical Activity: Manual Perforated Patch Clamp Application Protocol
- Ma et al (2011) High purity human-induced pluripotent stem cell-derived cardiomyocytes electrophysiological properties of action potentials and ionic currents
- Gibson et al (2014) Human stem cell-derived cardiomyocytes detect drug-mediated changes in action potentials and ion currents.