Merck 22nd Technology Symposium

This year’s 22nd Annual Merck Technology Symposium provides a networking forum for over 900 Merck scientists, with talks and posters, supplemented by a supplier trade show with over 100 exhibitors. The meeting will be organized around several tracks illustrating the various ways that technologies are facilitating scientific decision making at Merck.

Winner of the 2014 Nobel Prize in Chemistry, Dr. Eric Betzig will present as this year’s Keynote speaker – "Imaging Cellular Structure and Dynamics from Molecules to Organisms". Dr. Betzig is currently a Senior Fellow at UC Berkeley, Janelia Research Campus, and the Howard Hughes Medical Institute.

Come visit Fujifilm Cellular Dynamics at Booth 407 and learn how human stem cell-derived tissue cells can advance your research in drug discovery, toxicology and disease modeling.

Join us for a Product Theater Talk

Thursday, September 6,  12:45 pm | Atlantic Ballroom

TitleThe Generation and Functional Characterization of Human Microglia from Episomally Reprogrammed iCell® Hematopoietic Progenitor Cells

Speaker: Simon Hilcove, PhD - Fujifilm Cellular Dynamics

Abstract: Microglia maintain immunological balance within the central nervous system by decreasing inflammation due to injury and buildup of cytotoxic substances and infectious material. Microglia research has been largely confined to rodents because human primary microglia are difficult to acquire and stably maintain in culture conditions. Here, we describe the generation, functional characterization and cryopreservation of human induced pluripotent stem cell-derived microglia (iMGL) from episomally reprogrammed iCell® Hematopoietic Progenitor Cells (proprietary technology) under defined conditions based on technology developed by the Blurton-Jones laboratory exclusively licensed to FCDI from the University of California-Irvine. iMGL retain purity, secrete immunomodulatory cytokines and phagocytose pHrodo-labelled bacterial bioparticles and amyloid beta (Aβ) fibrils. The ability to produce essentially limitless quantities of iMGL holds great promise for accelerating human neuroscience research into the role of microglia in normal and diseased states.




Start: 2018-09-05

End: 2018-09-06


Venue: Ocean Place Resort and Spa
1 Ocean Blvd
Long Branch, NJ 07740 United States