Searching and Ordering from the CIRM iPSC Repository
The lines in the CIRM iPSC Repository have been organized into a searchable index. Using the CIRM search tool, you can:
- Customize your search parameters to identify specific lines that match your research objective.
- Search using simple text to find lines based on your chosen keyword.
- See family relationships for available samples.
- Filter for disease category and further narrow disease type to see only disease-specific lines and controls.
- Filter for affected status to see either disease samples or their corresponding control lines.
- Show or hide and sort on any of the sample data parameters.
- Download the entire data set or selected subset data in your desired file format including .csv (comma-separated values), .xlsx (Excel file format), and PDF. Or simply copy to the clipboard or print your selections.
- Easily add selections to a cart (including selection from multiple clones where applicable).
- Transfer all selected lines and quantities to the purchase page and complete the purchase process.
Search, Sort, and Filter Tools
Disease Selection
The CIRM iPSC lines have been grouped by disease category and by subtype where applicable. For example, if you select Liver Disease, you will see only samples and controls for the iPSC lines in the collection that relate to liver diseases. From there, you can select from HCV, NASH, steatosis, or control lines by selecting or deselecting the option check boxes. Where applicable, you can select two disease options to filter samples matching both selections. Options for selection are as follows:
Disease | Type | Description |
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Liver Disease | HCV | Hepatitis C |
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NASH | Nonalcoholic Steatohepatitis | |
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Steatosis (not NASH) | ||
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Controls | Unaffected for diseases in this category | |
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Neurodevelopmental Disorders | ASD | Autism Spectrum Disorder |
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Cerebral Palsy | ||
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Intellectual Disability | ||
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Epilepsy | ||
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Controls | Unaffected for diseases in this category | |
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Cardiomyopathy | Hypertrophic | |
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Dilated | ||
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Left Ventricular Non-compaction | ||
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Arrhythmogenic Right Ventricular | ||
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Restrictive | ||
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Other | See clinical data for these samples | |
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Lung Disease | Idiopathic Pulmonary Fibrosis | |
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Other | Control samples include self-reported COPD, Asthma, Emphysema | |
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Control | Unaffected for diseases in this category | |
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Alzheimer’s | Alzheimer’s | |
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Control | Unaffected for diseases in this category | |
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Blinding Eye Diseases | Age-related Macular Degeneration | |
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Diabetic Retinopathy | ||
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Diabetes Type I | ||
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Diabetes Type II | ||
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Diabetes Type Unknown | ||
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Glaucoma/POAG | Primary Open-angle Glaucoma | |
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Other | See clinical data for these samples | |
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Control | Unaffected for diseases in this category | |
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Disease Status
For any set of displayed of iPSC lines, you can filter only for affected, unaffected, or all samples (the default setting).
Note: If you select only control lines using a Disease selector and then choose Affected for Disease Status, you will not see any displayed lines because these two options are mutually exclusive.
Family Status
If you are interested in iPSC lines sampled from sibling or parent/child combinations or are looking for only samples from unrelated individuals, the Family Status drop-down permits the displayed iPSC lines to be filtered on that basis.
Other Selectors
There are other drop-down selectors for Race, Ethnicity, and Sex. These filter the entire set of displayed lines based on the setting selected.
Age Range Sliders
You can narrow the age range for samples based on Age at Sampling, Age at Diagnosis, and Age at Onset.
Note: For any samples where the corresponding data were not provided, the samples will be removed from the displayed lines.
Seeing Familial Relationship Among Lines
When a sample has another family member available within the collection, the family icon (shown right) will be displayed. By clicking this icon (displayed in column 2 under default settings), you can see all related family samples and their relationship. In this example, clicking the Show Related icon for CW60391 reveals two other related samples, CW60391 and CW60389.
Displaying Available Clinical Data
Clicking on the Show Clinical icon (shown right) will reveal the available clinical data for that sample. The complete clinical data sets are available for download here.
Column Visibility and Exporting Data
For any displayed set of lines based on the filters selected, you can export the data to a variety of formats including .csv (comma-separated values), .xlsx (Excel file format), and PDF. Or simply copy the displayed data to the clipboard. There are many additional columns available beyond what are displayed when the default page loads. You can toggle on or off individual columns for display using the Column visibility drop-down. Any columns set to visible will also be exported as described above.
Adding items to Cart
Clicking on any row will add that line to your cart. The selected row will be highlighted to indicate it has been selected and the corresponding line will appear in the cart information near the top of the page.
You can remove samples from the cart by either clicking the remove icon or clicking on the highlighted item in the table to deselect it.
Note: For some lines, there are more than one clone available. You can select either available clone (or both) by checking the box adjacent to the letter. These individual clones from the same donor were processed in parallel.
Completing and Placing the Order
When you have added all desired items to the cart and are ready to complete the order, click the Order Selected Items button.
Your selected items, along with the desired quantity, will be transferred to the CIRM order form. Because the terms for purchase require a non-negotiable Material Transfer Agreement and commercial organizations also require a license, the order form initiates the purchase process but does not process payment. After all lines and purchase information have been submitted, FCDI Customer Support will verify any required documentation and contact you to complete the purchase process.