Can I use iCell Cardiomyocytes to start cultures for hypoxia models?

Yes. iCell® Cardiomyocytes recapitulate the biochemical, electrophysiological, mechanical, and pathophysiological properties of native human cardiac myocytes, you can use these for a variety of applications including hypoxia. Our Application Protocol describes how to induce and quantify hypoxia in iCell Cardiomyocytes as a human-based in vitro model of cardiac ischemia.

For more information about hypertrophy models, see solutions 00000037D,  00000050A00000050B00000050C00000050D, and 00000050E

References:

  1. iCell Cardiomyocytes - What's New
  2. iCell Cardiomyocytes User's Guide
  3. Application Protocol: Modeling Cardiac Ischemia: Hypoxia Induction for Cardioprotection Screening