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May 2021EventsPublications
FCDI
Events

BlueRock Therapeutics, FUJIFILM Cellular Dynamics & Opsis Therapeutics Enter into a Strategic R&D Alliance to Discover & Develop Cell Therapies for Eye Diseases

The newly formed alliance will develop off-the-shelf iPS cell therapies for ocular diseases, including dry age-related macular degeneration (AMD) and inherited retinal diseases, containing human retinal pigment epithelial cells and photoreceptor cells.

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FUJIFILM Cellular Dynamics
Events
FUJIFILM Cellular Dynamics

ISSCR 2021 Virtual

Join FCDI for ISSCR 2021 Virtual and these events:

Talk: Common Non-Scientific Challenges in The Generation, Use and Sharing of iPSC Lines

Poster Presentations:

  • Investigating the Role of the AD Protective CD33 Variant in the Context of APOE Genotype Using hiPSC-Derived Microglia
  • Scalable Expansion Culture of Human Induced Pluripotent Stem Cells Using Microcarriers
  • Microfluidic High-Throughput Screening Platform to Screen Pre-Clinical Stage Compound Effects on Neurite Outgrowth of Human Motor Neurons Post Injury 

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Publications

Design of Synthetic Promoters for Controlled Expression of Therapeutic Genes in Retinal Pigment Epithelial Cells

Johari YB, Mercer AC, Liu Y, Brown AJ, James DC. Biotechnol Bioeng. 2021 May;118(5):2001-2015. Epub 2021 Mar 3.

See this paper describing progress towards gene therapy for blinding eye diseases. The group designed and tested synthetic promoters with RPE cell specificity. Their work suggests that optimized synthetic promoters can be optimized for cell specific gene transcription, a vital step in the treatment of AMD and other eye diseases.

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FUJIFILM Cellular Dynamics

FUJIFILM Cellular Dynamics

Improving Reliability and Reducing Costs of Cardiotoxicity Assessments Using Laser-Induced Cell Poration on Microelectrode Arrays

Iachetta G, Colistra N, Melle G, Deleye L, Tantussi F, De Angelis F, Dipalo M. Toxicol Appl Pharmacol. 2021 May 1;418:115480. Epub 2021 Mar 6.

Learn about an innovative approach to drug cardiotox detection using laser-induced optoacoustic poration with CMOS-MEA technology. The described approach enables the acquisition of high-quality action potential recordings from large numbers of cardiomyocytes within the same culture well, providing reliable data using a single-well MEA device.

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Events

Culturing and Assaying Calcium Transients of 3D Cardiac Tri-Culture Microtissues

See the latest Application Protocol from FCDI describing a 3D, multi-cellular system containing iCell® Cardiomyocytes, iCell Endothelial Cells, and primary cardiac fibroblasts with the potential for even greater physiological relevance, predictive power, and mechanistic insight than cardiomyocytes alone. 3D microtissues offer a simple and physiologically relevant approach to recapitulate in vivo heart biology. See the protocol for full details.

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FUJIFILM Cellular Dynamics

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